Matrixyl 3000®

Matrixyl 3000®

INCI Name:

  • Palmitoyl Tripeptide-1
  • Palmitoyl Tetrapeptide-7


Matrixyl 3000 is an active peptide-based ingredient clinically proven to lift & firm the skin and significantly reduce the appearance of wrinkles. It is a combination of two matrikines (derived from small endogenous peptides conjugated with palmitic acid for better delivery) that act as cell messengers to stimulate the process of skin repair.


Matrixyl 3000 was developed by the Sederma corporation, and it combines two lipo-peptides that help to improve the health of the skin cells while increasing the skin's extracellular matrix (the skin's structural framework) protein production. By regulating cell activity, elevating collagen synthesis, promoting elastin production, and delaying cell deterioration, this peptide duo repairs wrinkled skin, increases skin elasticity, and balances skin tone.

Peptides are small protein fragments representing short chains of amino acids that can help promote the health or structure of a cell. The two peptides in Matrixyl include Palmitoyl tripeptide-1 (also known as Palmitoyl oligopeptide or Pal-GHK) and Palmitoyl tetrapeptide-7.

products containing Matrixyl 3000® active ingredient:
  • Extract of young tea leaves, rich in antioxidants such as catechins and polyphenols.

  • Menthol is an ingredient known for its cooling and soothing effects in skin care and pharmaceutical products.